SSBSS 2017

Recent advances in DNA synthesis have increased our ability to build biological systems. Synthetic Biology aims at streamlining the design and synthesis of robust and predictable biological systems using engineering design principles. Designing biological systems requires a deep understanding of how genes and proteins are newcastl and interact in living cells: Systems Biology aims at elucidating the cellular organization at gene, protein and network level using computational and biochemical methods.

The Synthetic and Systems Biology Summer School (SSBSS) is a full-immersion five-day residential summer school at the Robinson College, University of Cambridge, UK on cutting-edge advances in systems and synthetic biology with lectures delivered by world-renowned experts. The school provides a stimulating environment for students (from Master students to PhD students), Post-Docs, early career researches, academics and industry leaders. Participants will also have the chance to present their results, and to interact with their peers, in a friendly and constructive environment.

Organization by Cambridge Systems Biology Centre - University of Cambridge, UK, TaoSciences Research Centre and Interdisciplinary Centre of Advanced Studies (ICAS).

Facebook: SSBSS. Email: info@icas.cc

• Computational Synthetic Biology
• Genetic Engineering
• Metabolic Engineering
• Reading and Writing Genomes
• Synthetic Genomes
• Synthetic Circuits and Cells
• Artificial Tissues and Organs
• Genomically Recoded Organisms
• Genome Design
• Pathway Design
• Biological Design Automation and Biological CAD

• Computational Systems Biology
• Genome Engineering
• Cellular Systems Biology
• Experimental Synthetic Biology
• Computational Synthetic Biology
• Stochastic Gene Regulation
• Gene Signaling
• Quantitative Molecular Biology
• High-throughput Techniques
• Biological Engineering
• Industrial Synthetic and Systems Biology

Lecturers

• Antonino Cattaneo, Scuola Normale Superiore Pisa, Italy
• Carole Goble, University of Manchester, UK
• Jim Haseloff, University of Cambridge, UK
• Jay Keasling, University of California, Berkeley, USA Lawrence Berkeley National Laboratory, USA Joint BioEnergy Institute, USA
• Edda Klipp, Humboldt University, Germany
• Natalio Krasnogor - Harold Fellermann, Centre for Synthetic Biology and Bioexploitation, Newcastle University, UK
• Markus Ralser, Cambridge Systems Biology Centre, University of Cambridge, UK & The Francis Crick Institute London, UK
• Uwe Sauer, Institute of Molecular Systems Biology, ETH Zurich, Switzerland
• Gill Stephens, The University of Nottingham, UK
• Mike Stubbington, EMBL-EBI, Cambridge UK
• Eriko Takano, Manchester Synthetic Biology Research Centre, University of Manchester, UK
• Sarah Teichmann, Wellcome Trust Sanger Institute & EMBL, European Bioinformatics Institute, UK

Courses

• Antonino Cattaneo, Scuola Normale Superiore Pisa, Italy
Lecture 1: "Synthetic Immunology I: Immune System in Vitro and Ectopic Expression of Antibodies"
Lecture 2: "Synthetic immunology II: Targeting the Post-Translational Proteome with Intrabodies"


• Carole Goble, University of Manchester, UK
Lecture 1: "Being FAIR: FAIR Data and Model Management"
Lecture 2: "Being Reproducible: Research Objects and R* Brouhaha"


• Jim Haseloff, University of Cambridge, UK
Lecture 1: "Analysis and Engineering of Microbial Systems"
Lecture 2: "Lower Plants as Simple Models for Bioengineering"


• Jay Keasling, University of California, Berkeley, USA Lawrence Berkeley National Laboratory, USA Joint BioEnergy Institute, USA
Lecture 1: "Synthetic Biology for Synthetic Chemistry"
Lecture 2: "Engineering Biology for Sustainable Development"


• Edda Klipp, Humboldt University, Germany
Lecture 1: "Yeast Mating in Space and Time"
Lecture 2: "Determinants of Yeast Cell Size in Individual Cells and for a Population"


• Natalio Krasnogor - Harold Fellermann, Centre for Synthetic Biology and Bioexploitation, Newcastle University, UK
Lecture 1: "Computational Synthetic Biology"
Lecture 2: "Looking Beyond Logic Gates"


• Markus Ralser, Cambridge Systems Biology Centre, University of Cambridge, UK & The Francis Crick Institute London, UK
Lecture 1: "The origin and evolution of the early metabolic network"
Lecture 2: "Functional Metabolomics: From metabolic signatures to the annotation of gene function to address the genotype-phenotype problem"


• Uwe Sauer, Institute of Molecular Systems Biology, ETH Zurich, Switzerland
Lecture 1: "Metabolomics as a Hypothesis Generator"
Lecture 2: "Coordination of Metabolism Through Metabolite-Protein Interactions"


• Gill Stephens, The University of Nottingham, UK
Lecture 1: "Synthetic biology for bio-based chemicals - Part 1"
Lecture 2: "Synthetic biology for bio-based chemicals - Part 2"


• Mike Stubbington, EMBL-EBI, Cambridge UK
Lecture : "Human Cell Atlas Project"


• Eriko Takano, Manchester Synthetic Biology Research Centre, University of Manchester, UK
Lecture 1: "Harnessing synthetic biology for fine and speciality chemical production ? Part I: Context and concepts"
Lecture 2: "Harnessing synthetic biology for fine and speciality chemical production ? Part II: Tools and applications"


• Sarah Teichmann, Wellcome Trust Sanger Institute & EMBL, European Bioinformatics Institute, UK
Lecture: "Understanding Cellular Heterogeneity"

Talks

• Matteo Barberis, University of Amsterdam, The Netherlands
Talk : "Deciphering Cell Cycle Robustness by a Novel Molecular Design Synchronizing its Dynamics and by a Multi-Scale Framework Integrating Cell Cycle and Metabolism in Budding Yeast"

• Jorge Julvez, Cambridge Systems Biology Centre & Department of Biochemistry - University of Cambridge, UK and Department of Computer Science and Systems Engineering - University of Zaragoza, Zaragoza, Spain
Talk : "Modelling, Analysing and Controlling Biological Systems by Flexible Nets"

Industrial Panel

• Thomas.Hofmeister, Thermo Fisher Scientific Inc., USA
Talk: "Driving Next Generation Biological Research By Synthetic Biology Tools and its Challenges for IT"

Workshop

The Synthetic and Systems Biology Summer School is the leading Summer School for sharing the state-of-the-art developments and achievements made in the fields of synthetic and systems biology.

SSBSS 2017 will focus on advances in the science and technology emerging from the fields of synthetic biology, systems biology, genome synthesis and genetic engineering. The School and the Workshop will highlight new tool development, as well as the application of these tools to diverse problems in biotechnology, computational medicine, molecular biology including therapeutics, industrial chemicals and biofuels, natural products, and agriculture.

If you are engaged in above cited research areas you must consider submitting.

Goal

Given the rapidity with which this field moves, it is challenging for both newcomers and experts alike to stay updated with all of the latest advances. The goal of this summer school and workshop is to bring together scientists from academia and industry with diverse but relevant expertise in a setting conducive to discussion of new results and potential collaborative efforts. Invited talks will cover a wide range of topics ranging from fundamental basic science through to applications. Attendees of this workshop will have the opportunity to hear about the latest findings in this fast-paced field and to establish collaborations with scientists who have complementary expertise.

Topics

Sessions integrate the recent achievements made in the fields of synthetic biology, systems biology, control engineering for synthetic biology, biochemical engineering, synthetic enzyme, evolutionary engineering, integrated omics, tools and methods, and emerging techniques, healthcare, biofuels, chemicals and materials, biologics, microbial and mammalian systems, and other disciplines and applications.

Submissions should be related to the following areas of synthetic biology, systems biology, genome and genetic engineering:

• Applications of Synthetic & Systems Biology
• Biological Design Automation
• Computational/Mathematical Modeling and Design
• Computer Aided Design
• Directed Evolution
• Designing and Writing Genomes
• DNA Synthesis, Assembly, and Sequencing
• High Throughput Design Space Exploration
• Industrial Applications of Synthetic & Systems Biology
• Mammalian Synthetic Biology
• Metabolic Engineering
• Microbial Synthetic Biology / Microbiome Engineering
• Molecular Programming
• Omics Science and Synthetic & Systems Biology
• Pedagogical/Educational Tools
• Plant Synthetic Biology
• Protein Engineering
• Synthetic & Systems Biology for Cell Culture and Medical Applications
• Synthetic & Systems Biology of Industrial Microorganisms

SSBSS 2017 Directors

Massimo Gulisano, University of Catania, Italy
Giuseppe Nicosia, University of Cambridge, UK
Steve G. Oliver, University of Cambridge, UK

School Director

Giuseppe Nicosia, University of Cambridge, UK

Organizing Committee

Piero Conca, CNR, Italy
Jole Costanza, Italian Institute of Technology, Italy
Giorgio Jansen, University of Catania, Italy
Giuseppe Narzisi, New York Genome Center, USA
Andrea Patane', University of Oxford, UK
Andrea Santoro, Queen Mary University London, UK
Renato Umeton, Dana-Farber Cancer Institute, USA
Luca Zammataro, Yale University, USA

Scientific Committee

Giuseppe Nicosia, University of Catania, Italy
Richard Allmendinger, The University of Manchester, UK
Matteo Barberis, University of Amsterdam, The Netherlands
Yaakov (Kobi) Benenson, Synthetic Biology Group@Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland
Leonidas Bleris, Bioengineering Department, The University of Texas at Dallas, USA
Paola Branduardi, University of Milano Bicocca, Italy
Michele Ceccarelli, University of Sannio, Italy
Jole Costanza, Italian Institute of Technology, Italy
Domitilla Del Vecchio, Department of Mechanical Engineering, MIT, USA
Diego Di Bernardo, Telethon Institute of Genetics & Medicine TIGEM & University of Napoli "Federico II", Italy
Barbara Di Camillo, University of Padova, Italy
Barbara Di Ventura, Synthetic Biology Group - BioQuant/DKFZ, Heidelberg, Germany
Simone Furini, University of Siena, Italy
Emanuele Domenico Giordano, University of Bologna, Italy
J. Gootenberg, Feng Zhang and Aviv Regev Groups, Department of Systems Biology, Harvard Medical School, Harvard University, USA
Guido Grandi, University Trento, Italy
Mario Guarracino, ICAR-CNR, Italy
Markus Herrgard, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Denmark
Paolo Magni, University of Pavia, Italy
Donato Malerba University of Bari, Italy
Vincenzo Manca, University of Verona, Italy
Nelson Marmiroli, University of Parma, Italy
Giancarlo Mauri, University of Milano Bicocca and SYSBIO - Center of Systems Biology, Italy
Enzo Medico, IRCC - Candiolo and University of Torino, Italy
Giuseppe Narzisi, New York Genome Center, USA
Wieslaw Nowak, Nicholas Copernicus University, Poland
Gennaro Piccialli, University of Napoli Federico II, Italy
Danilo Porro, University of Milano Bicocca, Italy
Francesco Ricci, University of Rome "Tor Vergata", Italy
Nicola Segata, University of Trento, Italy
Gianna Maria Toffolo, University of Padova, Italy
Renato Umeton, Dana-Farber Cancer Institute, USA
Luca Zammataro, Yale University, USA

The SSBSS 2017 Best Presentations

• Yarrowia lipolytica as a synthetic biology chassis for the production of fuels and chemicals
  Rodrigo Ledesma-Amaro, Jean-Marc Nicaud
  INRA, France


• Towards living devices - electrode engineering for photo-bioelectric interfaces with biofilms
  Tobias Wenzel, Paolo Bombelli, Daniel Haertter, Christopher Howe, Ullrich Steiner
  University of Cambridge, UK


• Single-cell analysis reveals the dynamic behaviour of Salmonella-macrophage interactions
  Marta Andres-Terre, Keara Lane, Takamasa Kudo, Markus Covert, Denise Monack
  Stanford University, USA


• Engineering of Yeast Cell Factories for Production of Adipic Acid from Municipal Solid Waste
  Ksenia Chekina, Vratislav Stovicek, Irina Borodina
  The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Denmark


• Sequential Bottom-up Assembly of Functional Cell-Like Compartments using Microfluidics
  Marian Weiss, Johannes Patrick Frohnmayer, Lucia Theresa Benk, Barbara Haller, Jan-Willi Janiesch, Ilia Platzman, Joachim P. Spatz
  Max-Planck Institute of Medical Research, Germany

Platinum Sponsors:

University of Cambridge, UK

Gold Sponsors:

TaoSciences Research Centre

Silver Sponsors:

TeselaGen Biotechnology Inc.

Bronze Sponsors:

In Silico Biology Journal

Next Edition

• The 5th International Synthetic and Systems Biology Summer School - SSBSS 2018, 25 - 29 July, 2018, Certosa di Pontignano (Siena) Tuscany - Italy.

Previous Editions

• 3rd International Synthetic and Systems Biology Summer School - SSBSS 2016, 8 - 14 July 2016, Volterra (Pisa) Tuscany, Italy.
• 2nd International Synthetic and Systems Biology Summer School - SSBSS 2015, 5 - 9 July 2015, Taormina - Sicily, Italy.
• 1st International Synthetic and Systems Biology Summer School - SSBSS 2014, 15 - 19 June 2014, Taormina - Sicily, Italy.